Brain/MINDs is making a connection map of marmoset cortex based on tracer injection with virus vectors. Three groups, led by Tetsuo Yamamori, Noritaka Ichinohe, and Partha Mitra, are involved. Yamamori group uses serial two-photon tomography (STPT) for imaging the projections while Ichinohe and Mitra groups both use a digital slide scanner. For accurate 3D registration, all the tracer-injected brains are also imaged with the MRI-scanner before sectioning. The tracer signals are going to be mapped to a reference 3D space, which will be used for integration of cross-modal experiments, including MRI, DTI and histological staining in addition to tracer data. We want to compare fiber tracks revealed by tracer injections and DTI imaging, which is being done by the above three and Dr. Okano’s groups, respectively.

Yamamori Lab, RIKEN BSI

Ichinohe Team, RIKEN BSI & National Institute of Neuroscience

Mitra Team, RIKEN BSI & Cold Spring Herbor Laboratory